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Indium (111In) capromab pendetide : ウィキペディア英語版 | Indium (111In) capromab pendetide
Indium (111In) capromab pendetide (trade name Prostascint) is used to image the extent of prostate cancer. Capromab is a mouse monoclonal antibody which recognizes prostate specific membrane antigen (PSMA) from prostate cancer cells and normal prostate tissue. It is linked to pendetide, a derivative of DTPA.〔(WHO Drug Information )〕 Pendetide acts as a chelating agent for the radionuclide indium-111. Following an intravenous injection of Prostascint, imaging is performed using single photon emission computed tomography (SPECT).〔 Early trials with yttrium (90Y) capromab pendetide were also conducted. == References ==
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